Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 3/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14832184 | 0.83 | ALOX5 (0.59) | ALOX5BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL9249815 | 0.80 | IDH1 (0.68) | ALOX5BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL27292714 | 0.80 | ALOX5 (0.55) | ALOX5BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL29712512 | 0.80 | CSNK2A1 (0.46) | ALOX5BACE1ALDH1A1CSNK2A1FOLH1 | |
| SCHEMBL11017739 | 0.80 | TRPA1 (0.57) | ALOX5BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL2807447 | 0.80 | CSNK2A1 (0.65) | ALOX5BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL3912942 | 0.80 | CSNK2A1 (0.70) | ALDH1A1HPGDHSD17B10CSNK2A1FOLH1 | |
| SCHEMBL27828641 | 0.78 | ALDH1A1 (0.48) | ALOX5BACE1ALDH1A1CSNK2A1FOLH1 | |
| SCHEMBL27828637 | 0.78 | CSNK2A1 (0.44) | ALOX5BACE1CSNK2A1FOLH1ESR2 | |
| SCHEMBL13957118 | 0.78 | CSNK2A1 (0.49) | ALOX5BACE1ALDH1A1HSD17B10CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563063-A | The method of 2, the 3- dihydro -1- benzofuran derivatives of 4- substitution is prepared by the cyclisation of 2- (phenyl that 2- diazonium -6 replaces) ethylate | 拜耳作物科学股份公司 | 2019-04-02 | — | — | CN | disclosed |
| US-4308407-A | Chemical process | ETHYL CORPORATION (US) | 1981-12-29 | — | — | US | disclosed |