Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11364497 | 1.00 | PKM (0.37) | PKMSMN1; SMN2LMNAUSP2MEN1 | |
| SCHEMBL11372617 | 0.82 | NOTUM (0.42) | PKMSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11372632 | 0.82 | NOTUM (0.42) | PKMSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL10948526 | 0.82 | ITGB3 (0.36) | PKMSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10948533 | 0.82 | ITGB3 (0.36) | PKMSMN1; SMN2LMNAMEN1KMT2A | |
| Bromide SCHEMBL10954610 | 0.81 | ITGB3 (0.36) | PKMSMN1; SMN2LMNAMEN1KMT2A | |
| Bromide SCHEMBL10954600 | 0.81 | ITGB3 (0.36) | PKMSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL11365870 | 0.80 | CRHBP (0.41) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL11365865 | 0.80 | CRHBP (0.41) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL11362034 | 0.80 | MEN1 (0.38) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262005-A | CONTROLLING ECTOPARASITES WHICH ATTACK CATTLE AND PIGS | THE BOOTS COMPANY LIMITED (GB) | 1981-04-14 | — | — | US | disclosed |