Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718835 | 0.87 | ESR1 (0.55) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL4517176 | 0.83 | L3MBTL1 (0.49) | GAAMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL11623145 | 0.83 | MMP8 (0.49) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL7625059 | 0.81 | FAAH (0.46) | ESR1SMN1; SMN2LMNAHTT | |
| SCHEMBL11117708 | 0.81 | ESR1 (0.52) | GAAESR1ESR2KMT2AMAPT | |
| SCHEMBL11362749 | 0.81 | CYP2C9 (0.48) | GAAESR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11361851 | 0.80 | GAA (0.40) | GAAESR1ESR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11358293 | 0.80 | TAAR1 (0.42) | GAAESR1ESR2KMT2AKDM4E | |
| SCHEMBL13084199 | 0.79 | GAA (0.44) | GAAESR1ESR2MEN1KMT2A | |
| SCHEMBL6293 | 0.79 | MAPT (0.46) | GAAMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4278680-A | Hypoglycaemically and hypolipidaemically active derivatives of phenylacetic acid | BOEHRINGER MANNHEIM GMBH (DE) | 1981-07-14 | — | — | US | disclosed |
| US-4207341-A | Hypoglycaemically and hypolipidaemically active derivatives of phenylacetic acid | BOEHRINGER-MANNHEIM GMBH (DE) | 1980-06-10 | — | — | US | disclosed |