Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380905 | 0.83 | NPC1 (0.38) | ALDH1A1NPC1RAB9APOLBHTT | |
| SCHEMBL11381035 | 0.81 | LMNA (0.37) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL11374925 | 0.79 | ALDH1A1 (0.36) | ALDH1A1KDM4ENPC1RAB9AHTT | |
| SCHEMBL11370333 | 0.78 | TSHR (0.43) | ALDH1A1NPC1RAB9APOLBHTT | |
| SCHEMBL11384148 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HSD17B10POLBHTTSMN1; SMN2 | |
| SCHEMBL11369008 | 0.75 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL11369404 | 0.74 | LMNA (0.70) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL11381141 | 0.73 | MAPT (0.47) | HTTSMN1; SMN2KMT2AMEN1CYP2C19 | |
| SCHEMBL11371323 | 0.73 | NPC1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL11369994 | 0.72 | ALDH1A1 (0.38) | ALDH1A1HPGDPOLBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271308-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4120864-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1978-10-17 | — | — | US | disclosed |