Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381035 | 0.86 | LMNA (0.37) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11370333 | 0.84 | TSHR (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11368779 | 0.83 | ALDH1A1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11380768 | 0.80 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11374925 | 0.78 | ALDH1A1 (0.36) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11371323 | 0.78 | NPC1 (0.50) | NPC1RAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL11384148 | 0.78 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL11373235 | 0.76 | RAB9A (0.57) | NPC1RAB9AALDH1A1KMT2APOLB | |
| SCHEMBL9972652 | 0.75 | — | — | |
| SCHEMBL11378240 | 0.75 | ALDH1A1 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271308-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4120864-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1978-10-17 | — | — | US | disclosed |