Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28507735 | 0.79 | GAA (0.44) | GAAKDM4EKMT2ADCUN1D1EPHX1 | |
| SCHEMBL9002880 | 0.79 | GAA (0.47) | GAAMTNR1AMTNR1BKDM4EKMT2A | |
| SCHEMBL6827159 | 0.78 | FLT3 (0.40) | KMT2AEPHX1EPHX2 | |
| SCHEMBL11361096 | 0.78 | ABL1 (0.39) | ABL1RIN1KDM4EKMT2AEPHX2 | |
| SCHEMBL10719771 | 0.77 | SMN1; SMN2 (0.44) | GAAALDH1A1 | |
| SCHEMBL11158681 | 0.76 | TEAD1 (0.46) | GAAKDM4EKMT2ADRD4SIGMAR1 | |
| SCHEMBL11477683 | 0.76 | EZH2 (0.53) | GAAKDM4EKMT2ADRD4SIGMAR1 | |
| SCHEMBL11163648 | 0.74 | MEN1 (0.43) | KMT2ASIGMAR1 | |
| SCHEMBL9456562 | 0.74 | KMT2A (0.60) | KMT2AUBE2MDCUN1D1EPHX1EPHX2 | |
| SCHEMBL9300647 | 0.73 | SIGMAR1 (0.43) | GAAMTNR1AMTNR1BKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294949-A | ACRYLATES OR ACRYLAMIDES WHICH CARRY N-HETEROCYCLIC RINGS | CIBA-GEIGY CORPORATION (US) | 1981-10-13 | — | — | US | disclosed |
| US-4276401-A | N-Heterocyclic substituted acryloyl polymeric compounds | CIBA-GEIGY CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |
| US-4256627-A | COMPRISING COMPLEXES OF POLYMERS HAVING UNITS CONTAINING ALKYLPIPERIDINE GROUPS AND NICKEL OR COBALT CARBOXYLATES OR ENOLATES | CIBA-GEIGY CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4210612-A | LIGHT STABILIZERS FOR PLASTICS | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
| EP-0010518-A1 | Acrylic copolymers bearing N-heterocyclic side rings, their use, and process for their preparation | CIBA-GEIGY AG (CH) | 1980-04-30 | — | — | EP | disclosed |