SCHEMBL9002880

SCHEMBL9002880

CC1(C)CC(NC(=O)C(=O)NN)CC(C)(C)N1Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.47
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 1/20 0.40
AMPD2 Q01433 2/20 0.39
DRD4 P21917 1/20 0.39
SIGMAR1 Q99720 2/20 0.39
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
EPHX1 P07099 1/20 0.37
EPHX2 P34913 1/20 0.37
GRM6 O15303 1/20 0.37
PLA2G2A P14555 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9300647 0.86 SIGMAR1 (0.43) GAAKMT2AKDM4ESIGMAR1MTNR1A
SCHEMBL28507735 0.85 GAA (0.44) GAAKMT2AALDH1A1SMN1; SMN2KDM4E
SCHEMBL11477683 0.82 EZH2 (0.53) GAAKMT2ASMN1; SMN2KDM4EDRD4
SCHEMBL11656694 0.80 AMPD2 (0.39) GAAKMT2AALDH1A1KDM4EAMPD2
SCHEMBL9456562 0.80 KMT2A (0.60) KMT2AALDH1A1SMN1; SMN2DRD4SIGMAR1
SCHEMBL11158681 0.80 TEAD1 (0.46) GAAKMT2AALDH1A1KDM4EDRD4
SCHEMBL11479436 0.79 DRD4 (0.47) GAAKMT2ASMN1; SMN2KDM4EDRD4
SCHEMBL11369331 0.79 ABL1 (0.42) GAAKMT2AALDH1A1KDM4EDRD4
SCHEMBL9002978 0.78 EZH2 (0.40) GAAKMT2ASMN1; SMN2KDM4EEPHX1
SCHEMBL11136955 0.76 CXCR3 (0.41) GAAKMT2AAMPD2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9238609-B2 Dicarboxylic acid monomers and methods of making and using the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-01-19 US disclosed
US-20150336869-A1 DICARBOXYLIC ACID MONOMERS AND METHODS OF MAKING AND USING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-26 US disclosed
WO-2015171709-A1 AMORPHOUS POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-12 WO disclosed
US-20150322200-A1 AMORPHOUS POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-12 US disclosed
US-8633265-B2 UV stabilization of isosorbide polycarbonates SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-01-21 US disclosed
EP-2665775-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC Innovative Plastics IP B.V. (NL) 2013-11-27 EP disclosed
WO-2012098513-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-26 WO disclosed
US-20120184651-A1 UV Stabilization of Isosorbide Polycarbonates SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-07-19 US disclosed
EP-0303279-B1 Reactive hindered amine light stabilizers ATOCHEM NORTH AMERICA ELF (US) 1996-09-25 EP disclosed
EP-0410970-B1 REACTIVE HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA ELF (US) 1996-08-14 EP disclosed
EP-0410970-A1 REACTIVE HINDERED AMINE LIGHT STABILIZERS. ATOCHEM NORTH AMERICA (US) 1991-02-06 EP disclosed
US-4983738-A For polymers ATOCHEM NORTH AMERICA, INC. (US) 1991-01-08 US disclosed
US-4978699-A Reaction product of hindered amine with primary amine or reactive hydrazide group and halogenated cyclic anhydride; for extrusion with polymers ATOCHEM NORTH AMERICA, INC. (US) 1990-12-18 US disclosed
US-4975489-A Heating an anhydride-containing polymer with a hydrazine derivative of a 2,2,6,6-tetramethyl-4-aminopiperidine in an inert solvent of by melt blending ATOCHEM NORTH AMERICA, INC. (US) 1990-12-04 US disclosed
EP-0366057-A2 Light stabilizing flame retardants ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) 1990-05-02 EP disclosed
US-4857595-A Polymer bound hindered amine light stabilizers PENNWALT CORPORATION (US) 1989-08-15 US disclosed
US-4824884-A Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers PENNWALT CORPORATION (US) 1989-04-25 US disclosed
EP-0303987-A2 Polymer bound hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303279-A2 Reactive hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed
EP-0303282-A2 Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336869-A1 DICARBOXYLIC ACID MONOMERS AND METHODS OF MAKING AND USING THE SAME PGD, CDA, PPIA GAA 995/4885KMT2A 1712/4885ALDH1A1 902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.