Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | DRD3 | P35462 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CYP2J2 | P51589 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456709 | 0.89 | HRH1 (0.74) | HRH1KCNH2LMNADRD3HTR2A | |
| SCHEMBL5999809 | 0.87 | HRH1 (0.79) | HRH1KCNH2LMNADRD3HTR2A | |
| SCHEMBL1968090 | 0.87 | HRH1 (0.79) | HRH1KCNH2LMNADRD3HTR2A | |
| SCHEMBL5999820 | 0.87 | HRH1 (0.79) | HRH1KCNH2LMNADRD3HTR2A | |
| Hydrochloric Acid SCHEMBL11365096 | 0.86 | HRH1 (0.79) | HRH1KCNH2LMNADRD3HTR2A | |
| SCHEMBL11377990 | 0.86 | HRH1 (0.72) | HRH1KCNH2LMNADRD3HTR2A | |
| Terfenadine SCHEMBL8187662 | 0.84 | LMNA (0.77) | HRH1KCNH2LMNADRD3HTR2A | |
| Methane SCHEMBL6327150 | 0.84 | HRH1 (0.52) | HRH1KCNH2LMNADRD3HTR2A | |
| SCHEMBL11376047 | 0.84 | CYP2J2 (0.58) | HRH1KCNH2LMNADRD3HTR2A | |
| SCHEMBL11365553 | 0.82 | HRH1 (0.71) | HRH1KCNH2LMNADRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285957-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4254129-A | ANTIALLERGENS, BRONCHODILATORS, ANTIHISTAMINES; 4-DIPHENYLMETHYL PIPERIDINO-ALKANOLS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |