Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.74 |
| ▸ | TTR | P02766 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485574 | 0.88 | AKR1B1 (0.70) | AKR1B1TTRKMT2AKDM4EMEN1 | |
| SCHEMBL11371017 | 0.86 | AKR1B1 (1.00) | AKR1B1TTRLMNAKMT2AKDM4E | |
| SCHEMBL11859643 | 0.80 | AKR1B1 (0.88) | AKR1B1TTRLMNAKMT2AKDM4E | |
| SCHEMBL11375812 | 0.80 | AKR1B1 (0.64) | AKR1B1TTRKMT2AKDM4EMEN1 | |
| SCHEMBL11866371 | 0.78 | AKR1B1 (0.65) | AKR1B1TTRKMT2AKDM4EMEN1 | |
| SCHEMBL11861274 | 0.77 | AKR1B1 (0.67) | AKR1B1TTRLMNAKMT2AKDM4E | |
| SCHEMBL11371242 | 0.76 | AKR1B1 (0.70) | AKR1B1TTRKMT2AKDM4EMEN1 | |
| SCHEMBL11861511 | 0.76 | AKR1B1 (0.69) | AKR1B1TTRKMT2AKDM4EMEN1 | |
| SCHEMBL68189 | 0.75 | TTR (0.83) | AKR1B1TTRKMT2AKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL11377674 | 0.75 | AKR1B1 (0.61) | AKR1B1LMNAL3MBTL1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250097-A | (7-METHYL(2-HYDROXYETHYL)AMINO)SULFONYLXANTHONE-2-CARBOXYLIC ACID; ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1981-02-10 | — | — | US | claimed |
| US-4232040-A | XANTHONE CARBOXYLIC ACIDS | SYNTEX (U.S.A.) INC. (US) | 1980-11-04 | — | — | US | disclosed |