Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.70 |
| ▸ | TTR | P02766 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.45 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369983 | 0.88 | AKR1B1 (0.74) | AKR1B1TTRSMN1; SMN2HPGDGAA | |
| SCHEMBL11866371 | 0.84 | AKR1B1 (0.65) | AKR1B1TTRSMN1; SMN2HPGDGAA | |
| SCHEMBL11371017 | 0.83 | AKR1B1 (1.00) | AKR1B1TTRSMN1; SMN2HPGDGAA | |
| SCHEMBL11375812 | 0.81 | AKR1B1 (0.64) | AKR1B1TTRHPGDRAB9ACA2 | |
| SCHEMBL11861274 | 0.81 | AKR1B1 (0.67) | AKR1B1TTRSMN1; SMN2HPGDGAA | |
| SCHEMBL11371242 | 0.78 | AKR1B1 (0.70) | AKR1B1TTRHPGDRAB9AKDM4E | |
| SCHEMBL11768920 | 0.77 | AKR1B1 (0.55) | AKR1B1TTRSMN1; SMN2HPGDGAA | |
| SCHEMBL68189 | 0.77 | TTR (0.83) | AKR1B1TTRSMN1; SMN2HPGDRAB9A | |
| SCHEMBL11859643 | 0.77 | AKR1B1 (0.88) | AKR1B1TTRSMN1; SMN2HPGDGAA | |
| Hydrochloric Acid SCHEMBL11476319 | 0.76 | AKR1B1 (0.49) | AKR1B1SMN1; SMN2HPGDGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4232040-A | XANTHONE CARBOXYLIC ACIDS | SYNTEX (U.S.A.) INC. (US) | 1980-11-04 | — | — | US | disclosed |