Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 4/20 | 0.62 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.62 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.62 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.62 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.62 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.62 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.62 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.62 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.62 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.62 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.62 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.62 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6,7-Dichloro-3-Hydroxy-2-Quinoxalinecarboxylic Acid SCHEMBL6697845 | 0.77 | GRIN2D (1.00) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL29778151 | 0.77 | GRIN2D (0.54) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL29037515 | 0.77 | GRIN2D (0.54) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL28444260 | 0.77 | HPGD (0.69) | LMNASMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL9705832 | 0.73 | GRIN2D (0.74) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL11364390 | 0.72 | GRIN2D (0.63) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL6306264 | 0.72 | GRIN2D (0.58) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL7345144 | 0.71 | GRIN2D (0.62) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL6658945 | 0.71 | GRIN2D (0.61) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9703926 | 0.70 | GRIN2D (0.74) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264600-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| EP-0010426-A1 | Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |