Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 6/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 6/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.58 |
| ▸ | GRIN2C | Q14957 | 6/20 | 0.58 |
| ▸ | GRIN3A | Q8TCU5 | 6/20 | 0.58 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.58 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.58 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.58 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.58 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.58 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.58 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.58 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11370785 | 0.81 | GRIN2D (0.56) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7345144 | 0.81 | GRIN2D (0.62) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6304037 | 0.79 | HRH4 (0.56) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6311370 | 0.79 | ALDH1A1 (0.64) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6304503 | 0.78 | KDM4E (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8872580 | 0.78 | MEN1 (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5774932 | 0.77 | GRIN2D (0.54) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL316047 | 0.76 | ALDH1A1 (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL14765197 | 0.74 | MAPT (0.56) | KDM4EMEN1ALDH1A1CYP1A2MAPT | |
| SCHEMBL14764938 | 0.74 | PIN1 (0.56) | KDM4EALDH1A1CYP1A2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181724-A | Quinoxalinone compounds useful for expanding the lumina or air passages in mammals | THE UPJOHN COMPANY (US) | 1980-01-01 | — | — | US | claimed |
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |
| EP-1147094-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000042026-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-20 | — | — | WO | disclosed |