Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 5/20 | 0.62 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.62 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.62 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.62 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.62 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.62 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.62 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.62 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.62 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.62 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.62 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872580 | 0.81 | MEN1 (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6306264 | 0.81 | GRIN2D (0.58) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31495003 | 0.77 | ALDH1A1 (0.58) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5774932 | 0.77 | GRIN2D (0.54) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6304225 | 0.77 | MEN1 (0.65) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29037515 | 0.77 | GRIN2D (0.54) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29778151 | 0.77 | GRIN2D (0.54) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| 6,7-Dichloro-3-Hydroxy-2-Quinoxalinecarboxylic Acid SCHEMBL6697845 | 0.77 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9703926 | 0.75 | GRIN2D (0.74) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL20309828 | 0.75 | GAA (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504085-A | TREATING ISCHEMIA, ANOXIA, HYPOGLYCEMIA AND HEAD, SPINAL CORD TRAUMA | NOVO NORDISK A/S (DK) | 1996-04-02 | — | — | US | disclosed |
| EP-0633885-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993006103-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-04-01 | — | — | WO | disclosed |