Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11370401 | 1.00 | LMNA (0.52) | LMNADRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL11370008 | 0.88 | LMNA (0.48) | LMNADRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL11367862 | 0.86 | OPRM1 (0.42) | LMNADRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL11370562 | 0.85 | MAPK1 (0.48) | LMNAOPRM1SLC6A2SLC6A4MEN1 | |
| SCHEMBL11374567 | 0.85 | LMNA (0.46) | LMNADRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL11384482 | 0.85 | LMNA (0.46) | LMNADRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL11364843 | 0.84 | LMNA (0.54) | LMNADRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL11364846 | 0.84 | LMNA (0.54) | LMNADRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL11370920 | 0.83 | OPRM1 (0.40) | LMNADRD3OPRM1SLC6A2SLC6A4 | |
| SCHEMBL11370154 | 0.82 | LMNA (0.52) | LMNADRD3OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4291059-A | 1-PHENYLCYCLOPENTANOL ACYLATE ESTER AND ITS PREPARATION | GLAXO GROUP LIMITED (GB) | 1981-09-22 | — | — | US | claimed |