Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11370562 | 0.86 | MAPK1 (0.48) | OPRM1SLC6A2SLC6A4MAPK1GAA | |
| SCHEMBL11370401 | 0.83 | LMNA (0.52) | OPRM1SLC6A2SLC6A4MAPK1OPRL1 | |
| SCHEMBL11370403 | 0.83 | LMNA (0.52) | OPRM1SLC6A2SLC6A4MAPK1OPRL1 | |
| Fumaric Acid SCHEMBL11370914 | 0.73 | OPRM1 (0.37) | OPRM1OPRL1SIGMAR1 | |
| Fumaric Acid SCHEMBL11370917 | 0.73 | OPRM1 (0.37) | OPRM1OPRL1SIGMAR1 | |
| SCHEMBL11384482 | 0.72 | LMNA (0.46) | OPRM1SLC6A2SLC6A4LMNADRD3 | |
| SCHEMBL11370008 | 0.72 | LMNA (0.48) | OPRM1SLC6A2SLC6A4MAPK1LMNA | |
| SCHEMBL11367862 | 0.70 | OPRM1 (0.42) | OPRM1SLC6A2SLC6A4LMNADRD3 | |
| SCHEMBL11374567 | 0.69 | LMNA (0.46) | OPRM1SLC6A2SLC6A4LMNASIGMAR1 | |
| SCHEMBL11362437 | 0.69 | OPRL1 (0.42) | OPRM1SLC6A2SLC6A4OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4291059-A | 1-PHENYLCYCLOPENTANOL ACYLATE ESTER AND ITS PREPARATION | GLAXO GROUP LIMITED (GB) | 1981-09-22 | — | — | US | disclosed |