Methane

SCHEMBL11370411

C.CCN(Cc1cc(C(=O)NCCCCCOC(C)=O)cc(Br)c1N)C1CCCCC1.COc1ccc2ccccc2c1

nearest known ligand 0.37

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	DRD2	P14416	5/20	0.37

▸	DRD3	P35462	4/20	0.37

▸	DRD4	P21917	1/20	0.37

▸	SLC6A2	P23975	1/20	0.35

▸	SLC6A4	P31645	1/20	0.35

▸	MAPT	P10636	3/20	0.35

▸	GAA	P10253	1/20	0.35

▸	TP53	P04637	2/20	0.34

▸	MTNR1A	P48039	2/20	0.34

▸	MTNR1B	P49286	2/20	0.34

▸	NQO2	P16083	1/20	0.34

▸	MCHR1	Q99705	1/20	0.34

▸	ACHE	P22303	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Methane SCHEMBL11342768	0.97	MAPT (0.38)	DRD2DRD3DRD4SLC6A2SLC6A4
Methane SCHEMBL11359566	0.94	MTNR1A (0.35)	DRD2DRD3DRD4SLC6A2SLC6A4
Methane SCHEMBL11314925	0.91	ALDH1A1 (0.35)	DRD3SLC6A2SLC6A4
Methane SCHEMBL11305895	0.91	ALDH1A1 (0.35)	DRD3SLC6A2SLC6A4
Methane SCHEMBL11302737	0.90	ALDH1A1 (0.35)	DRD3SLC6A2SLC6A4
Methane SCHEMBL11301610	0.89	ALDH1A1 (0.35)	DRD3SLC6A2SLC6A4MAPT
Methane SCHEMBL11291301	0.87	ALDH1A1 (0.36)	SLC6A2SLC6A4MTNR1AMTNR1BNQO2
Methane SCHEMBL11290482	0.87	ALDH1A1 (0.34)	SLC6A2SLC6A4MTNR1AMTNR1BNQO2
Methane SCHEMBL11359227	0.85	DRD2 (0.37)	DRD2DRD3DRD4SLC6A2SLC6A4
Methane SCHEMBL11376025	0.85	DRD2 (0.37)	DRD2DRD3DRD4SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4362738-A	ANTIINFLAMMATORIES	DR. KARL THOMAE GMBH (DE)	1982-12-07	—	—	US	disclosed