Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 8/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11590123 | 0.94 | TSHR (0.41) | TSHRNCEH1THRATHRBHSD17B10 | |
| SCHEMBL10483081 | 0.92 | TSHR (0.38) | TSHRALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10662827 | 0.82 | TSHR (0.34) | TSHRNCEH1HSD17B10ALDH1A1LMNA | |
| SCHEMBL11562192 | 0.81 | TSHR (0.39) | TSHRNCEH1HSD17B10ALDH1A1LMNA | |
| Ethiofencarb SCHEMBL74938 | 0.79 | ALDH1A1 (0.49) | TSHRTHRATHRBHSD17B10ALDH1A1 | |
| Ethiofencarb SCHEMBL6738022 | 0.79 | ALDH1A1 (0.49) | TSHRTHRATHRBHSD17B10ALDH1A1 | |
| Ethiofencarb SCHEMBL29449861 | 0.79 | ALDH1A1 (0.49) | TSHRTHRATHRBHSD17B10ALDH1A1 | |
| SCHEMBL11373035 | 0.79 | TSHR (0.42) | TSHRNCEH1THRATHRBHSD17B10 | |
| SCHEMBL11191166 | 0.78 | CYP3A4 (0.37) | ALDH1A1MAPTRAB9A | |
| Ethiofencarb SCHEMBL7528780 | 0.76 | ALDH1A1 (0.46) | TSHRHSD17B10ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264625-A | INSECTICIDES, MITICIDES, NEMATOCIDES | UNION CARBIDE CORPORATION (US) | 1981-04-28 | — | — | US | disclosed |