Ethiofencarb

Ethiofencarb

SCHEMBL7528780

CCSCc1ccccc1OC(=O)NC.CNC(=O)O

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
PGR P06401 1/20 0.46
GAA P10253 1/20 0.46
PTGS1 P23219 1/20 0.46
MAPK1 P28482 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ACHE P22303 1/20 0.46
LMNA P02545 1/20 0.39
ALOX5 P09917 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
TSHR P16473 1/20 0.36
HPGD P15428 1/20 0.36
EPHX1 P07099 1/20 0.36
CYP1A2 P05177 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethiofencarb SCHEMBL6738022 0.96 ALDH1A1 (0.49) ALDH1A1PGRGAAPTGS1MAPK1
Ethiofencarb SCHEMBL29449861 0.96 ALDH1A1 (0.49) ALDH1A1PGRGAAPTGS1MAPK1
Ethiofencarb SCHEMBL74938 0.96 ALDH1A1 (0.49) ALDH1A1PGRGAAPTGS1MAPK1
Ethiofencarb SCHEMBL8382113 0.90 ALDH1A1 (0.40) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL11796469 0.89 ALDH1A1 (0.46) ALDH1A1PGRGAAPTGS1MAPK1
Ethiofencarb SCHEMBL28835316 0.84 TSHR (0.37) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL9326227 0.80 ALDH1A1 (0.57) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL31105729 0.80 ALDH1A1 (0.57) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL27280817 0.78 AKR1B1 (0.46) ALDH1A1LMNATSHRHPGDMEN1
SCHEMBL11712280 0.77 ALDH1A1 (0.48) ALDH1A1PGRGAAPTGS1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906014-B1 Shaped bodies which release agrochemicals BAYER AG (DE) 2002-03-27 EP disclosed
EP-0906014-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES BAYER AG (DE) 1999-04-07 EP disclosed
EP-0861024-A1 POLYSACCHARIDE ETHER ESTERS WHICH RELEASE ACTIVE INGREDIENTS BAYER AG (DE) 1998-09-02 EP disclosed
WO-1997046094-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-11 WO disclosed
WO-1997017847-A1 POLYSACCHARIDE ETHER ESTERS WHICH RELEASE ACTIVE INGREDIENTS BAYER AKTIENGESELLSCHAFT (DE) 1997-05-22 WO disclosed
EP-0124404-A1 Insecticide collar and method for its manufacture Rombi, Max André (FR) 1984-11-07 EP disclosed