Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11370599 | 0.81 | TSHR (0.43) | TSHRALDH1A1NCEH1SMN1; SMN2HSD17B10 | |
| SCHEMBL11562777 | 0.80 | ALDH1A1 (0.42) | TSHRALDH1A1NCEH1MEN1KMT2A | |
| SCHEMBL11562709 | 0.80 | ALDH1A1 (0.49) | TSHRALDH1A1NCEH1KMT2ALMNA | |
| SCHEMBL11590123 | 0.79 | TSHR (0.41) | TSHRALDH1A1NCEH1SMN1; SMN2HSD17B10 | |
| SCHEMBL11559999 | 0.79 | HSD17B10 (0.48) | ALDH1A1NCEH1MEN1KMT2AHSD17B10 | |
| SCHEMBL10483081 | 0.75 | TSHR (0.38) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11567127 | 0.73 | MEN1 (0.43) | TSHRNCEH1MEN1KMT2ALMNA | |
| SCHEMBL11563702 | 0.73 | L3MBTL1 (0.34) | TSHRNCEH1MEN1KMT2ALMNA | |
| SCHEMBL11561373 | 0.71 | LMNA (0.55) | ALDH1A1MEN1KMT2ALMNA | |
| Ethiofencarb SCHEMBL6738022 | 0.71 | ALDH1A1 (0.49) | TSHRALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179514-A | INSECTICIDES, MITICIDES, NEMATOCIDES | UNION CARBIDE CORPORATION (US) | 1979-12-18 | — | — | US | disclosed |
| US-4081550-A | KETOALKANESULFENYL AND KETOALKANETHIOSULFENYL CARBAMATES | UNION CARBIDE CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |