Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | CYP27A1 | Q02318 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378122 | 0.83 | TYR (0.46) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11370827 | 0.81 | TYR (0.46) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11152447 | 0.80 | TYR (0.57) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10951204 | 0.80 | TYR (0.57) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11383981 | 0.78 | TYR (0.56) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10943070 | 0.75 | TYR (0.44) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4324078 | 0.75 | ALDH1A1 (0.55) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1429142 | 0.75 | ALDH1A1 (0.55) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8927334 | 0.74 | ALOX5 (0.51) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10950763 | 0.73 | TYR (0.44) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288437-A | ANTICONVULSANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1981-09-08 | — | — | US | disclosed |