Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11350710 | 0.80 | PTGS2 (0.58) | PTGS2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL11369388 | 0.78 | PTGS2 (0.47) | PTGS2KMT2ALMNACYP2C9USP2 | |
| SCHEMBL11386345 | 0.78 | MEN1 (0.38) | PTGS2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL6950571 | 0.73 | TTR (0.67) | PTGS2KMT2ALMNACYP2C9USP2 | |
| SCHEMBL13800457 | 0.73 | TTR (0.67) | PTGS2KMT2ALMNACYP2C9USP2 | |
| SCHEMBL688218 | 0.73 | TTR (0.48) | PTGS2KMT2ALMNACYP2C9USP2 | |
| SCHEMBL11374498 | 0.71 | PTGS2 (0.49) | PTGS2KMT2AALDH1A1LMNACYP2C9 | |
| SCHEMBL11373541 | 0.69 | KMT2A (0.39) | PTGS2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL25720185 | 0.68 | PTGS2 (0.57) | PTGS2KMT2ALMNACYP2C9USP2 | |
| SCHEMBL13688511 | 0.68 | PTGS2 (0.66) | PTGS2KMT2ALMNACYP2C9USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272507-A | Phenylaminothiophenacetic acids, their synthesis, compositions and use | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-06-09 | — | — | US | disclosed |