Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380719 | 0.81 | PHGDH (0.30) | — | |
| SCHEMBL11351974 | 0.78 | MEN1 (0.51) | MEN1KMT2ALMNATDP1CYP3A4 | |
| SCHEMBL11371289 | 0.78 | PTGS2 (0.38) | MEN1KMT2ALMNATDP1CYP3A4 | |
| SCHEMBL13318490 | 0.70 | PTGS2 (0.44) | MEN1KMT2ALMNATDP1CYP3A4 | |
| SCHEMBL11374075 | 0.70 | KMT2A (0.42) | MEN1KMT2ALMNATDP1CYP2C9 | |
| SCHEMBL11380072 | 0.69 | PTGS2 (0.52) | MEN1KMT2ALMNATDP1CYP1A2 | |
| SCHEMBL11258911 | 0.69 | L3MBTL1 (0.50) | MEN1KMT2ATDP1CYP3A4CYP1A2 | |
| SCHEMBL11249841 | 0.69 | L3MBTL1 (0.50) | MEN1KMT2ATDP1CYP3A4CYP1A2 | |
| SCHEMBL11373706 | 0.68 | CXCL8 (0.43) | MEN1KMT2ALMNACYP2C9MAPT | |
| SCHEMBL10310896 | 0.68 | MT-CO2 (0.58) | MEN1KMT2ALMNATDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272507-A | Phenylaminothiophenacetic acids, their synthesis, compositions and use | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-06-09 | — | — | US | disclosed |