Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.59 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.59 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.59 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.59 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13800457 | 1.00 | TTR (0.67) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13299162 | 0.93 | TTR (0.73) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL26655363 | 0.92 | TTR (0.60) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL10310898 | 0.89 | TTR (0.65) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13109328 | 0.89 | TTR (0.65) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13299158 | 0.89 | TTR (0.65) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13299178 | 0.89 | TTR (0.65) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13777335 | 0.89 | TTR (0.65) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL14605848 | 0.88 | TTR (0.67) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL10116869 | 0.88 | TTR (0.70) | TTRCYP2C9USP2LMNATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403756-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-02 | — | — | US | disclosed |
| US-9403756-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-02 | — | — | US | disclosed |
| EP-2203411-B1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | UNIV RAMOT (IL) | 2016-01-06 | — | — | EP | disclosed |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-10-23 | — | — | US | disclosed |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-10-23 | — | — | US | disclosed |
| US-8765815-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-07-01 | — | — | US | disclosed |
| US-8765815-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-07-01 | — | — | US | disclosed |
| US-8278357-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-10-02 | — | — | US | disclosed |
| US-8278357-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-10-02 | — | — | US | disclosed |
| US-20120178785-A1 | DERIVATIVES OF N-PHENYLANTHRANILIC ACID AND 2-BENZIMIDAZOLONE AS POTASSIUM CHANNEL AND/OR NEURON ACTIVITY MODULATORS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-07-12 | — | — | US | disclosed |
| US-20090170934-A1 | MANUFACTURING PROCESS FOR NO-DONATING COMPOUNDS SUCH AS NO-DONATING DICLOFENAC | NICOX SA | 2009-07-02 | — | — | US | disclosed |
| US-20090096314-A1 | ELECTRIC MOTOR | HONDA MOTOR CO., LTD. (JP) | 2009-04-16 | — | — | US | disclosed |
| US-20090096314-A1 | ELECTRIC MOTOR | HONDA MOTOR CO., LTD. (JP) | 2009-04-16 | — | — | US | disclosed |
| WO-2009037707-A2 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009037705-A2 | ESTERS OF N-PHENYLANTHRANILIC ACID FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATION | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2009-03-26 | — | — | WO | disclosed |
| US-20030207919-A1 | Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use | NICOX S.A. (FR) | 2003-11-06 | — | — | US | disclosed |
| US-6593347-B2 | Especially a nitrosated and/or nitrosylated arylpropionic acid, arylacetic acid, enolic anilide or an oxicam | NITROMED, INC. | 2003-07-15 | — | — | US | disclosed |
| US-20020016322-A1 | Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositons and methods of use | NICOX S.A. (FR) | 2002-02-07 | — | — | US | disclosed |
| US-6297260-B1 | Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use | NITROMED, INC. | 2001-10-02 | — | — | US | disclosed |
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016322-A1 | Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositons and methods of use | NOS2, NOS3, NOS1 | TTR 129/4885CYP2C9 81/4885USP2 2602/4885 |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | TRPV1, TRPA1, TRPV4 | TTR 4167/4885CYP2C9 4025/4885USP2 4465/4885 |
| US-20120178785-A1 | DERIVATIVES OF N-PHENYLANTHRANILIC ACID AND 2-BENZIMIDAZOLONE AS POTASSIUM CHANNEL AND/OR NEURON ACTIVITY MODULATORS | KCNN2, KCNN1, KCNN3 | TTR 3939/4885CYP2C9 2597/4885USP2 4558/4885 |
| US-20090170934-A1 | MANUFACTURING PROCESS FOR NO-DONATING COMPOUNDS SUCH AS NO-DONATING DICLOFENAC | NOS2, NOS1, NOS3 | TTR 2002/4885CYP2C9 10/4885USP2 1318/4885 |
| US-20030207919-A1 | Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use | NOS2, NOS1, NOS3 | TTR 1206/4885CYP2C9 113/4885USP2 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.