SCHEMBL11372103

SCHEMBL11372103

CCCCS(=O)(=O)c1ncn(C(=O)N(CC)CCOC)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
PKM P14618 1/20 0.34
CYP2C19 P33261 1/20 0.34
MLYCD O95822 1/20 0.34
DPP4 P27487 2/20 0.33
CNR2 P34972 1/20 0.32
HTT P42858 2/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
MMP1 P03956 1/20 0.31
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
NAMPT P43490 1/20 0.30
ABL1 P00519 1/20 0.30
RIN1 Q13671 1/20 0.30
KDM4E B2RXH2 1/20 0.30
TP53 P04637 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11378979 0.94 CYP1A2 (0.34) CYP1A2CYP3A4CYP2C9PKMCYP2C19
SCHEMBL11366088 0.94 AHR (0.34) CYP1A2CYP3A4CYP2C9PKMCYP2C19
SCHEMBL11371730 0.94 DPP4 (0.33) CYP1A2CYP3A4CYP2C9PKMCYP2C19
SCHEMBL11375228 0.93 MLYCD (0.35) CYP1A2CYP3A4CYP2C9PKMCYP2C19
SCHEMBL11367515 0.92 DPP4 (0.33) CYP1A2CYP3A4CYP2C9PKMCYP2C19
SCHEMBL11372627 0.91 THRB (0.34) CYP1A2CYP3A4CYP2C9PKMCYP2C19
SCHEMBL11381395 0.91 ALDH1A1 (0.34) CYP1A2CYP3A4CYP2C9PKMCYP2C19
SCHEMBL11377364 0.91 KDM4E (0.34) CYP1A2CYP3A4CYP2C9PKMCYP2C19
SCHEMBL11377705 0.90 DPP4 (0.33) DPP4HTTALDH1A1MAPTMMP1
SCHEMBL11382975 0.90 DPP4 (0.33) DPP4HTTALDH1A1MAPTMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4251262-A 1-Carbamoyl-1,2,4-triazole herbicidal agents THE BOOTS COMPANY LIMITED (GB) 1981-02-17 US disclosed