Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11382091 | 0.91 | OPRK1 (0.49) | OPRD1OPRK1OPRM1CYP2J2HTR1A | |
| SCHEMBL11369771 | 0.86 | CYP2J2 (0.52) | OPRD1OPRK1OPRM1CYP2J2HTR1A | |
| SCHEMBL11373711 | 0.82 | OPRD1 (0.48) | OPRD1OPRK1OPRM1CYP2J2HTR1A | |
| SCHEMBL11384846 | 0.81 | OPRM1 (0.47) | OPRD1OPRK1OPRM1HTR1ADRD2 | |
| SCHEMBL11369436 | 0.80 | OPRM1 (0.41) | OPRD1OPRK1OPRM1CYP2J2HTR1A | |
| SCHEMBL11372307 | 0.80 | CYP2J2 (0.63) | CYP2J2DRD2HRH1HTR2ADRD3 | |
| SCHEMBL11543696 | 0.78 | CYP2J2 (0.63) | OPRD1OPRK1OPRM1CYP2J2HTR1A | |
| SCHEMBL11374333 | 0.78 | OPRD1 (0.52) | OPRD1OPRK1OPRM1HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL11828383 | 0.77 | CYP2J2 (0.62) | OPRD1OPRK1OPRM1CYP2J2HTR1A | |
| Hydrochloric Acid SCHEMBL11833697 | 0.77 | CYP2J2 (0.62) | OPRD1OPRK1OPRM1CYP2J2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285958-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4254130-A | ANTIALLERGENS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |