Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.44 |
| ▸ | PGK1 | P00558 | 4/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11586954 | 0.82 | LMNA (0.44) | PGK1PDE10AGSK3BMAP4K2LMNA | |
| SCHEMBL10992257 | 0.76 | NLRP3 (0.38) | TLR8PGK1NLRP3PDE10AGSK3B | |
| SCHEMBL15904104 | 0.72 | PDE10A (0.43) | TLR8PGK1PDE10AGSK3BMAP4K2 | |
| SCHEMBL11371734 | 0.71 | NUDT1 (0.40) | KDM4EALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13539690 | 0.71 | TLR8 (0.41) | TLR8PGK1NLRP3PDE10ALMNA | |
| SCHEMBL20164752 | 0.68 | LMNA (0.44) | TLR8PGK1NLRP3PDE10AKDM4E | |
| SCHEMBL30560037 | 0.68 | LMNA (0.44) | TLR8PGK1NLRP3PDE10AKDM4E | |
| SCHEMBL30560040 | 0.68 | LMNA (0.44) | TLR8PGK1NLRP3PDE10AKDM4E | |
| SCHEMBL11582545 | 0.68 | LMNA (0.38) | PGK1PDE10AGSK3BMAP4K2ALDH1A1 | |
| SCHEMBL6128041 | 0.66 | TLR8 (0.70) | TLR8NLRP3TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000681-B1 | AMINO-2 (OR -4) ALKYLTHIO-5 PYRIMIDINES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS HERBICIDES AND COMPOSITION CONTAINING THEM | P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1981-08-26 | — | — | EP | disclosed |
| EP-0000681-A1 | Amino-2 (or -4) alkylthio-5 pyrimidines, processes for their preparation, their use as herbicides and composition containing them | P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1979-02-07 | — | — | EP | disclosed |