Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.42 |
| ▸ | PTGFR | P43088 | 3/20 | 0.42 |
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380062 | 0.85 | MEN1 (0.44) | PTGER4PTGER3PTGFRHPGDPTGER1 | |
| SCHEMBL11377693 | 0.85 | HTT (0.40) | PTGER4PTGER2PTGER3PTGFRPTGIR | |
| SCHEMBL11625788 | 0.84 | PTGER2 (0.40) | PTGER4PTGER2PTGER3PTGFRPTGIR | |
| SCHEMBL10865234 | 0.83 | ALDH1A1 (0.55) | PTGER4PTGER2PTGER3PTGFRPTGIR | |
| SCHEMBL22489230 | 0.83 | TBXA2R (0.55) | PTGER4PTGER2PTGER3PTGFRPTGIR | |
| SCHEMBL11757808 | 0.83 | PTGER4 (0.55) | PTGER4PTGER2PTGER3PTGFRPTGIR | |
| SCHEMBL11484889 | 0.83 | PTGER4 (0.45) | PTGER4PTGER2PTGER3PTGFRPTGIR | |
| SCHEMBL10938627 | 0.83 | PTGER4 (0.55) | PTGER4PTGER2PTGER3PTGFRPTGIR | |
| SCHEMBL11730586 | 0.80 | PTGER3 (0.39) | PTGER4PTGER2PTGER3PTGFRPTGIR | |
| SCHEMBL11733161 | 0.80 | PTGER3 (0.39) | PTGER4PTGER2PTGER3PTGFRPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283417-A | ANTISECRETORY AGENTS | PFIZER INC. (US) | 1981-08-11 | — | — | US | disclosed |
| US-4268522-A | BRONCHODILATOR AGENTS, ANTISECRETORY AGENTS | PFIZER INC. (US) | 1981-05-19 | — | — | US | disclosed |