Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.43 |
| ▸ | PTGIR | P43119 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478005 | 0.87 | ALDH1A1 (0.53) | PTGER4PTGER3ALDH1A1KDM4EHKDC1 | |
| SCHEMBL11128286 | 0.83 | ALDH1A1 (0.47) | PTGER4PTGER3PTGER2ALDH1A1KDM4E | |
| SCHEMBL10865234 | 0.83 | ALDH1A1 (0.55) | PTGER4PTGER3PTGER2ALDH1A1PDE4D | |
| SCHEMBL11373350 | 0.83 | PTGER4 (0.42) | PTGER4PTGER3PTGER2ALDH1A1PDE4D | |
| SCHEMBL22489230 | 0.83 | TBXA2R (0.55) | PTGER4PTGER3PTGER2ALDH1A1PDE4D | |
| SCHEMBL11177219 | 0.82 | PDE4D (0.62) | PTGER4PTGER3ALDH1A1KDM4EHKDC1 | |
| SCHEMBL11115530 | 0.82 | PDE4D (0.62) | PTGER4PTGER3ALDH1A1KDM4EHKDC1 | |
| SCHEMBL10938627 | 0.82 | PTGER4 (0.55) | PTGER4PTGER3PTGER2ALDH1A1PDE4D | |
| SCHEMBL11757808 | 0.82 | PTGER4 (0.55) | PTGER4PTGER3PTGER2ALDH1A1PDE4D | |
| SCHEMBL11158708 | 0.81 | PDE4D (0.53) | PTGER4PTGER3ALDH1A1KDM4EHKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233222-A | Cyclopentylacetic acid derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-11-11 | — | — | US | disclosed |
| US-4210669-A | Prostanoic acid derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-07-01 | — | — | US | disclosed |