Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 10/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11364300 | 0.88 | TBK1 (0.47) | TBK1IKBKEPOLBNPC1RAB9A | |
| SCHEMBL11362855 | 0.88 | RAB9A (0.51) | TBK1IKBKEPOLBNPC1RAB9A | |
| SCHEMBL2907432 | 0.87 | TBK1 (0.56) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL11098702 | 0.87 | TBK1 (0.43) | TBK1IKBKEPOLBNPC1RAB9A | |
| SCHEMBL11369213 | 0.85 | TBK1 (0.42) | TBK1IKBKEPOLBNPC1RAB9A | |
| SCHEMBL11359964 | 0.85 | TBK1 (0.42) | TBK1IKBKEPOLBNPC1RAB9A | |
| SCHEMBL11550983 | 0.84 | POLB (0.43) | TBK1IKBKEPOLBNPC1RAB9A | |
| SCHEMBL11366969 | 0.84 | NPC1 (0.48) | TBK1POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11357243 | 0.83 | RAB9A (0.49) | TBK1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11356857 | 0.81 | TTR (0.56) | POLBNPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | claimed |
| US-4299963-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | disclosed |
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | disclosed |