Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11364824 | 0.90 | RAB9A (0.46) | SMN1; SMN2MAPTTBK1LMNARXFP1 | |
| SCHEMBL11364300 | 0.84 | TBK1 (0.47) | POLBSMN1; SMN2TBK1IKBKEMEN1 | |
| SCHEMBL11362855 | 0.84 | RAB9A (0.51) | POLBSMN1; SMN2MAPTTBK1IKBKE | |
| SCHEMBL11374157 | 0.84 | TBK1 (0.44) | POLBSMN1; SMN2TBK1IKBKELMNA | |
| SCHEMBL11098702 | 0.83 | TBK1 (0.43) | POLBSMN1; SMN2TBK1IKBKERXFP1 | |
| SCHEMBL2907432 | 0.83 | TBK1 (0.56) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11369213 | 0.81 | TBK1 (0.42) | POLBSMN1; SMN2MAPTTBK1IKBKE | |
| SCHEMBL11359964 | 0.81 | TBK1 (0.42) | POLBSMN1; SMN2TBK1IKBKELMNA | |
| SCHEMBL11368425 | 0.76 | TBK1 (0.46) | POLBSMN1; SMN2TBK1IKBKERXFP1 | |
| SCHEMBL11098672 | 0.76 | TBK1 (0.41) | POLBSMN1; SMN2TBK1IKBKERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | claimed |