Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11373996 | 0.88 | OPRM1 (0.47) | OPRM1OPRD1OPRK1OPRL1HSD17B10 | |
| SCHEMBL11370495 | 0.85 | OPRM1 (0.50) | OPRM1OPRD1OPRK1OPRL1HSD17B10 | |
| SCHEMBL11375882 | 0.82 | CYP3A4 (0.50) | OPRM1OPRD1OPRK1OPRL1SMAD3 | |
| SCHEMBL6979086 | 0.81 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OPRL1SMAD3 | |
| SCHEMBL11380355 | 0.79 | MEN1 (0.46) | OPRM1OPRD1OPRK1OPRL1HSD17B10 | |
| SCHEMBL11375998 | 0.78 | OPRD1 (0.48) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL11371103 | 0.78 | HSD17B10 (0.37) | OPRM1OPRD1OPRK1OPRL1HSD17B10 | |
| SCHEMBL11371100 | 0.78 | HSD17B10 (0.37) | OPRM1OPRD1OPRK1OPRL1HSD17B10 | |
| SCHEMBL11407430 | 0.75 | CYP19A1 (0.47) | OPRM1OPRD1OPRK1OPRL1SMAD3 | |
| SCHEMBL12444346 | 0.71 | CHRM2 (0.52) | OPRM1OPRD1OPRK1OPRL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267318-A | 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof | G. D. SEARLE & CO. (US) | 1981-05-12 | — | — | US | disclosed |