Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368361 | 0.87 | OPRM1 (0.56) | OPRD1OPRM1MGLLOPRK1OPRL1 | |
| SCHEMBL11369302 | 0.86 | MGLL (0.47) | OPRD1OPRM1MGLLOPRK1OPRL1 | |
| SCHEMBL11381493 | 0.81 | MEN1 (0.50) | OPRD1OPRM1MGLLOPRK1OPRL1 | |
| SCHEMBL11368410 | 0.81 | OPRD1 (0.42) | OPRD1OPRM1MGLLOPRK1OPRL1 | |
| SCHEMBL11368406 | 0.81 | OPRD1 (0.42) | OPRD1OPRM1MGLLOPRK1OPRL1 | |
| SCHEMBL6979086 | 0.80 | OPRM1 (0.51) | OPRD1OPRM1MGLLOPRK1OPRL1 | |
| SCHEMBL11377370 | 0.78 | SMN1; SMN2 (0.44) | OPRD1OPRM1MGLLOPRK1OPRL1 | |
| SCHEMBL11374255 | 0.78 | OPRM1 (0.45) | OPRD1OPRM1OPRK1OPRL1TSHR | |
| SCHEMBL11378101 | 0.77 | MCHR1 (0.47) | MAPT | |
| SCHEMBL11370495 | 0.74 | OPRM1 (0.50) | OPRD1OPRM1OPRK1OPRL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267318-A | 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof | G. D. SEARLE & CO. (US) | 1981-05-12 | — | — | US | disclosed |