Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 11/20 | 1.00 |
| ▸ | CYBB | P04839 | 2/20 | 1.00 |
| ▸ | NOX3 | Q9HBY0 | 2/20 | 1.00 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | GAA | P10253 | 6/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SNCA | P37840 | 3/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560225 | 1.00 | NOX1 (1.00) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL29475150 | 1.00 | NOX1 (1.00) | NOX1CYBBNOX3NOX4MAPT | |
| Benzene SCHEMBL29242186 | 0.98 | NOX1 (0.97) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL10372692 | 0.91 | NOX1 (0.84) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL30811565 | 0.91 | NOX1 (0.84) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL1855582 | 0.91 | NOX1 (0.83) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL25898787 | 0.83 | NOX1 (0.71) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL11375009 | 0.82 | NOX1 (0.69) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL8881132 | 0.82 | NOX1 (0.68) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL9007359 | 0.82 | NOX1 (0.68) | NOX1CYBBNOX3NOX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005020913-A2 | FORMULATIONS, CONJUGATES, AND COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS | COMBINATORX, INCORPORATED (US) | 2005-03-10 | — | — | WO | disclosed |