Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 1.00 |
| ▸ | SNCA | P37840 | 7/20 | 0.64 |
| ▸ | CYBB | P04839 | 1/20 | 0.59 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.59 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.59 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867073 | 0.86 | SNCA (0.79) | NOX1SNCAMAPTNPC1RAB9A | |
| SCHEMBL29214094 | 0.86 | SNCA (0.79) | NOX1SNCAMAPTNPC1RAB9A | |
| SCHEMBL1208092 | 0.83 | SNCA (0.84) | NOX1SNCAMAPTNPC1RAB9A | |
| SCHEMBL29625234 | 0.83 | SNCA (0.84) | NOX1SNCAMAPTNPC1RAB9A | |
| SCHEMBL3031049 | 0.80 | SNCA (0.68) | NOX1SNCAMAPTALDH1A1HSD17B10 | |
| SCHEMBL30769632 | 0.79 | SNCA (1.00) | NOX1SNCAMAPTALOX15NPC1 | |
| SCHEMBL239724 | 0.79 | SNCA (1.00) | NOX1SNCAMAPTALOX15NPC1 | |
| SCHEMBL20842835 | 0.78 | NOX1 (0.68) | NOX1SNCACYBBNOX3NOX4 | |
| SCHEMBL11375009 | 0.77 | NOX1 (0.69) | NOX1SNCACYBBNOX3NOX4 | |
| SCHEMBL14571431 | 0.76 | SNCA (0.72) | NOX1SNCAMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140308317-A1 | Polymeric Compounds And Methods Of Making And Using The Same | CELLCEUTIX CORPORATION (US) | 2014-10-16 | — | — | US | disclosed |
| US-20140308317-A1 | Polymeric Compounds And Methods Of Making And Using The Same | CELLCEUTIX CORPORATION (US) | 2014-10-16 | — | — | US | disclosed |
| WO-2014093225-A2 | POLYCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CELLCEUTIX CORPORATION (US) | 2014-06-19 | — | — | WO | disclosed |
| WO-2014093225-A2 | POLYCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CELLCEUTIX CORPORATION (US) | 2014-06-19 | — | — | WO | disclosed |
| WO-2004037192-A2 | IDENTIFICATION OF ANTIMYCOBACTERIAL TARGETS AND THE INHIBITION THEREOF AS A TREATMENT FOR INFECTIOUS DISEASES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308317-A1 | Polymeric Compounds And Methods Of Making And Using The Same | ALG1, CD44, MUC1 | NOX1 2473/4885SNCA 4861/4885CYBB 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.