Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.59 |
| ▸ | ACP3 | P15309 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16781986 | 0.80 | TDP1 (0.62) | CES2ACP3LMNAPNMTSRD5A2 | |
| SCHEMBL11503699 | 0.78 | CES2 (0.64) | CES2ACP3LMNASRD5A2MAOB | |
| SCHEMBL28423546 | 0.78 | CES2 (0.60) | CES2ACP3LMNASRD5A2MAOB | |
| SCHEMBL23031071 | 0.75 | CES2 (0.59) | CES2ACP3PNMTIDO1TDO2 | |
| SCHEMBL18409716 | 0.75 | CES2 (1.00) | CES2ACP3LMNAPNMTSRD5A2 | |
| SCHEMBL4077713 | 0.74 | CES2 (0.54) | CES2ACP3PNMTSRD5A2IDO1 | |
| SCHEMBL16781981 | 0.74 | CES2 (0.51) | CES2ACP3SRD5A2IDO1TDO2 | |
| SCHEMBL22193351 | 0.73 | PNMT (0.61) | CES2ACP3LMNAPNMTIDO1 | |
| SCHEMBL17843619 | 0.73 | CES2 (0.65) | CES2LMNAIDO1TDO2CES1 | |
| SCHEMBL16781987 | 0.73 | PTPN1 (0.54) | CES2ACP3LMNASRD5A2KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271319-A | Phenyl beta-chloro-alpha-hydroxy-beta-(3-trifluoromethylphenyl)ethyl ketone and process for its production | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1981-06-02 | — | — | US | claimed |
| US-4229378-A | Process for the production of 1-phenyl-3-(3-trifluoromethylphenyl)-2-propanone | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-10-21 | — | — | US | claimed |
| US-4271319-A | Phenyl beta-chloro-alpha-hydroxy-beta-(3-trifluoromethylphenyl)ethyl ketone and process for its production | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1981-06-02 | — | — | US | disclosed |
| US-4271319-A | Phenyl beta-chloro-alpha-hydroxy-beta-(3-trifluoromethylphenyl)ethyl ketone and process for its production | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1981-06-02 | — | — | US | disclosed |
| US-4271319-A | Phenyl beta-chloro-alpha-hydroxy-beta-(3-trifluoromethylphenyl)ethyl ketone and process for its production | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1981-06-02 | — | — | US | disclosed |
| US-4229378-A | Process for the production of 1-phenyl-3-(3-trifluoromethylphenyl)-2-propanone | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-10-21 | — | — | US | disclosed |
| US-4228085-A | Phenyl-alpha,beta-epoxy-beta-(3-trifluoromethylphenyl)ethyl ketone and process for its production | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-10-14 | — | — | US | disclosed |
| US-4212998-A | 1-Phenyl-3-(3-trifluoromethylphenyl)-2-propanol and process for its production | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-07-15 | — | — | US | disclosed |
| US-4212999-A | 1-Phenyl-3-(3-trifluoromethylphenyl)-1,2-propane diol and process for its production | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-07-15 | — | — | US | disclosed |