Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750908 | 0.83 | CES2 (0.56) | CES2SRD5A2MAOBACP3CNR2 | |
| SCHEMBL11753080 | 0.83 | CES2 (0.56) | CES2LMNASRD5A2MAOBACP3 | |
| SCHEMBL28669423 | 0.82 | CES2 (0.65) | CES2LMNASRD5A2MAOBKCNK3 | |
| SCHEMBL17483864 | 0.82 | CES2 (0.64) | CES2LMNASRD5A2MAOBKCNK3 | |
| SCHEMBL27873040 | 0.81 | CES2 (0.62) | CES2LMNASRD5A2MAOBKCNK3 | |
| SCHEMBL11753938 | 0.80 | CES2 (0.61) | CES2LMNAKCNK3GPR139OPRM1 | |
| SCHEMBL28423546 | 0.79 | CES2 (0.60) | CES2LMNASRD5A2MAOBGPR139 | |
| SCHEMBL11375046 | 0.78 | CES2 (0.59) | CES2LMNASRD5A2MAOBKCNK3 | |
| SCHEMBL18409716 | 0.78 | CES2 (1.00) | CES2LMNASRD5A2MAOBNPSR1 | |
| SCHEMBL458300 | 0.78 | TDP1 (0.61) | CES2LMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1979000858-A1 | DIARYL SUBSTITUTED PYROZOLINE CARBOXANILIDES,PROCESSES FOR PREPARING THEM,INSECTICIDAL COMPOSITIONS AND USES THEREOF,AND INTERMEDIATES THEREFOR | ICI LTD (GB) | 1979-11-01 | — | — | WO | disclosed |