Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 10/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.50 |
| ▸ | POLQ | O75417 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12305117 | 0.80 | CYP2A6 (0.47) | POLQABL1 | |
| SCHEMBL11178308 | 0.79 | MAP4K4 (0.54) | FYN | |
| SCHEMBL11381614 | 0.76 | RPS6KA3 (0.48) | HSD17B1HSD17B2CYP3A4CYP2C9CDC7 | |
| SCHEMBL10306739 | 0.76 | HSD17B1 (0.54) | HSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL21982143 | 0.76 | L3MBTL1 (0.46) | ADORA1CYP2C9ABL1GAAFYN | |
| SCHEMBL29914649 | 0.75 | HSD17B2 (0.66) | HSD17B1HSD17B2CYP3A4CYP2C9FYN | |
| SCHEMBL29431686 | 0.75 | HSD17B2 (0.66) | HSD17B1HSD17B2CYP3A4CYP2C9FYN | |
| SCHEMBL21228152 | 0.75 | HSD17B2 (0.66) | HSD17B1HSD17B2CYP3A4CYP2C9FYN | |
| SCHEMBL30186373 | 0.74 | HSD17B1 (0.79) | HSD17B1HSD17B2CYP3A4CYP2C9FYN | |
| SCHEMBL11373076 | 0.73 | CYP3A4 (0.50) | ADORA1CYP3A4ABL1GAAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4297363-A | 2-Amino-3(4 or 5)-(pyridinyl)phenols and their use as cardiotonics | STERLING DRUG INC. (US) | 1981-10-27 | — | — | US | disclosed |