Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | DPP4 | P27487 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15614381 | 0.83 | KMT2A (0.49) | KMT2AGAAALDH1A1DPP4LMNA | |
| SCHEMBL8234075 | 0.82 | KDM1A (0.46) | GAAALDH1A1LMNASMN1; SMN2KDM1A | |
| SCHEMBL11376853 | 0.82 | TSHR (0.38) | KMT2AGAAALDH1A1DPP4LMNA | |
| SCHEMBL11391648 | 0.81 | CYP4F2 (0.48) | KMT2AALDH1A1LMNAMAPTTSHR | |
| SCHEMBL11382501 | 0.80 | ALDH1A1 (0.50) | KMT2AGAAALDH1A1LMNAMAPT | |
| SCHEMBL11378325 | 0.80 | ALDH1A1 (0.50) | KMT2AGAAALDH1A1LMNAMAPT | |
| SCHEMBL2900687 | 0.77 | KMT2A (0.65) | KMT2AGAAALDH1A1DPP4LMNA | |
| SCHEMBL31609523 | 0.77 | DPP4 (0.42) | KMT2AGAAALDH1A1DPP4LMNA | |
| SCHEMBL11384531 | 0.77 | ALDH1A1 (0.48) | KMT2AGAAALDH1A1LMNAMAPT | |
| SCHEMBL22208862 | 0.76 | LCK (0.61) | KMT2AGAAALDH1A1DPP4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273773-A | IN COMBINATION WITH A DIURETIC | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-06-16 | — | — | US | disclosed |