Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259012 | 0.77 | KDM4E (0.53) | HTTMAPTALDH1A1GAAKDM4E | |
| SCHEMBL7981392 | 0.62 | SRC (0.61) | HTTMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL18888112 | 0.61 | HTT (0.46) | HTTMAPTALDH1A1HMGCRKDM4E | |
| SCHEMBL18054329 | 0.61 | ALDH1A1 (0.43) | MAPTALDH1A1MAPK1HPGDHSD17B10 | |
| SCHEMBL6132065 | 0.60 | PTPN11 (0.58) | MAPTALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL8840816 | 0.60 | MAOB (0.50) | HTTMAPTALDH1A1HMGCRGAA | |
| SCHEMBL11373100 | 0.60 | MEN1 (0.50) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL6208739 | 0.59 | MAPT (0.56) | RETHTTMAPTALDH1A1KDM4E | |
| SCHEMBL1003108 | 0.59 | NQO2 (0.63) | RETALDH1A1GAAKDM4EBRD4 | |
| SCHEMBL5337318 | 0.59 | MCL1 (0.54) | HTTMAPTALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273930-A | INTERMEDIATES FOR THE 4-ALKOXY ANTIALLERGENS | SANDOZ, INC. (US) | 1981-06-16 | — | — | US | disclosed |
| US-4190659-A | ANTIALLERGENS, ANTIHISTAMINES | SANDOZ, INC. (US) | 1980-02-26 | — | — | US | disclosed |
| US-4119720-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1978-10-10 | — | — | US | disclosed |