Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 7/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.63 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | BRD1 | O95696 | 1/20 | 0.52 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.52 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | S100B | P04271 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17576471 | 0.87 | NQO2 (0.53) | NQO2CYP19A1BRD9BRD4BRD1 | |
| SCHEMBL17576470 | 0.87 | S100B (0.57) | NQO2CYP19A1BRD9BRD4BRD1 | |
| SCHEMBL7983553 | 0.76 | S100B (0.44) | NQO2CYP19A1KDM4EALDH1A1GLA | |
| SCHEMBL392780 | 0.76 | NQO2 (0.57) | NQO2CYP19A1BRD9KDM4EALDH1A1 | |
| SCHEMBL1001961 | 0.76 | NQO2 (0.59) | NQO2CYP19A1KDM4EALDH1A1HPGD | |
| SCHEMBL24716706 | 0.74 | NQO2 (0.55) | NQO2CYP19A1BRD9BRD4BRD1 | |
| SCHEMBL14873828 | 0.74 | CYP19A1 (0.77) | NQO2CYP19A1BRD9KDM4EALDH1A1 | |
| SCHEMBL27240400 | 0.74 | CYP19A1 (0.41) | NQO2CYP19A1BRD9KDM4EALDH1A1 | |
| SCHEMBL19448883 | 0.73 | ATAD2 (0.56) | NQO2CYP19A1BRD9BRD4BRD1 | |
| SCHEMBL19448884 | 0.73 | NQO2 (0.53) | NQO2CYP19A1BRD9BRD4BRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731960-B2 | Biheterocyclic compound | Sumitomo Pharma Co., Ltd. (JP) | 2023-08-22 | — | — | US | disclosed |
| US-20220380353-A1 | BIHETEROCYCLIC COMPOUND | Sumitomo Pharma Co., Ltd. (JP) | 2022-12-01 | — | — | US | disclosed |
| US-20210198242-A1 | BIHETEROCYCLIC COMPOUND | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-07-01 | — | — | US | disclosed |
| US-10870642-B2 | Biheterocyclic compound | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-12-22 | — | — | US | disclosed |
| US-20190308958-A1 | BIHETEROCYCLIC COMPOUND | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2019-10-10 | — | — | US | disclosed |
| US-10323024-B2 | Biheterocyclic compound | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2019-06-18 | — | — | US | disclosed |
| US-20190016711-A1 | BIHETEROCYCLIC COMPOUND | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2019-01-17 | — | — | US | disclosed |
| US-9382425-B2 | Aza-benzazolium containing cyanine dyes | Life Technologies Corporation (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150031579-A1 | Aza-Benzazolium Containing Cyanine Dyes | MOLECULAR PROBES, INC. | 2015-01-29 | — | — | US | disclosed |
| US-8883415-B2 | Aza-benzazolium containing cyanine dyes | Life Technologies Corporation (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130178395-A1 | Aza-Benzazolium Containing Cyanine Dyes | Life Technologies Corporation (US) | 2013-07-11 | — | — | US | disclosed |
| US-20120295817-A1 | Aza-benzazolium Containing Cyanine Dyes | Life Technologies Corporation (US) | 2012-11-22 | — | — | US | disclosed |
| US-8252530-B2 | Aza-benzazolium containing cyanine dyes | Life Technologies Corporation (US) | 2012-08-28 | — | — | US | disclosed |
| US-20110217696-A1 | AZA-BENZAZOLIUM CONTAINING CYANINE DYES | Life Technologies Corporation (US) | 2011-09-08 | — | — | US | disclosed |
| US-7871773-B2 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | Life Technologies Corporation (US) | 2011-01-18 | — | — | US | disclosed |
| US-20080044811-A1 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | INVITROGEN CORPORATION (US) | 2008-02-21 | — | — | US | disclosed |
| US-7226740-B2 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | INVITROGEN CORPORATION (US) | 2007-06-05 | — | — | US | disclosed |
| US-20040137475-A1 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | Life Technologies Corporation | 2004-07-15 | — | — | US | disclosed |
| US-6664047-B1 | Assymetrical; substituted by a cationic side chain; exhibit bright fluorescence when associated with nucleic acid polymers such as DNA or RNA, or with polypeptides | MOLECULAR PROBES, INC. | 2003-12-16 | — | — | US | disclosed |
| WO-2000066664-A1 | AZA-BENZAZOLIUM CONTAINING CYANINE DYES | MOLECULAR PROBES, INC. (US) | 2000-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040137475-A1 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | POLL, IK, ADAR | NQO2 1987/4885CYP19A1 4702/4885BRD9 707/4885 |
| US-20110217696-A1 | AZA-BENZAZOLIUM CONTAINING CYANINE DYES | AZI2, BRDT, DNMT1 | NQO2 2000/4885CYP19A1 4391/4885BRD9 59/4885 |
| US-20220380353-A1 | BIHETEROCYCLIC COMPOUND | NPY4R, NR4A3, OGFR | NQO2 2073/4885CYP19A1 434/4885BRD9 490/4885 |
| US-11731960-B2 | Biheterocyclic compound | NR4A3, NGF, OGFR | NQO2 2217/4885CYP19A1 450/4885BRD9 465/4885 |
| US-20210198242-A1 | BIHETEROCYCLIC COMPOUND | NR4A3, NGF, OGFR | NQO2 2217/4885CYP19A1 450/4885BRD9 465/4885 |
| US-20190308958-A1 | BIHETEROCYCLIC COMPOUND | NR4A3, NGF, OGFR | NQO2 2217/4885CYP19A1 450/4885BRD9 465/4885 |
| US-10323024-B2 | Biheterocyclic compound | NR4A3, NGF, OGFR | NQO2 2217/4885CYP19A1 450/4885BRD9 465/4885 |
| US-10870642-B2 | Biheterocyclic compound | NR4A3, NGF, OGFR | NQO2 2217/4885CYP19A1 450/4885BRD9 465/4885 |
| US-20190016711-A1 | BIHETEROCYCLIC COMPOUND | NR4A3, NGF, OGFR | NQO2 2217/4885CYP19A1 450/4885BRD9 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.