Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372258 | 0.94 | TBXAS1 (0.42) | TBXAS1QPCTCYP19A1ALOX15SMN1; SMN2 | |
| SCHEMBL11372576 | 0.90 | NR1I3 (0.45) | NR1I3CYP19A1 | |
| SCHEMBL11373650 | 0.89 | EGLN3 (0.46) | TBXAS1EGLN3CYP19A1SMN1; SMN2 | |
| SCHEMBL11372860 | 0.88 | ACHE (0.39) | TBXAS1NR1I3EGLN3ALDH1A1 | |
| SCHEMBL11377610 | 0.86 | ACHE (0.39) | TBXAS1EGLN3ALDH1A1CYP19A1 | |
| SCHEMBL11158189 | 0.86 | MEN1 (0.40) | TBXAS1EGLN3ALDH1A1SMN1; SMN2 | |
| SCHEMBL11372168 | 0.86 | KDM4E (0.41) | TBXAS1EGLN3ALDH1A1CYP19A1 | |
| SCHEMBL11383874 | 0.86 | EGLN3 (0.38) | TBXAS1EGLN3ALDH1A1SMN1; SMN2 | |
| SCHEMBL11381987 | 0.85 | ACHE (0.42) | TBXAS1ALDH1A1CYP19A1 | |
| SCHEMBL11377618 | 0.84 | ACHE (0.39) | TBXAS1NR1I3EGLN3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289768-A | HYPOTENSIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-09-15 | — | — | US | disclosed |