Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.47 |
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375289 | 0.89 | EP300 (0.50) | EP300MEN1KMT2ACYP2C19ELANE | |
| SCHEMBL14656853 | 0.78 | EP300 (0.51) | EP300MEN1KMT2ACYP2C19ELANE | |
| SCHEMBL5252516 | 0.77 | MEN1 (0.53) | EP300MEN1KMT2ACYP2C19ELANE | |
| SCHEMBL7839682 | 0.74 | LMNA (0.36) | EP300MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7847859 | 0.74 | ALDH1A1 (0.52) | EP300MEN1KMT2ACYP2C19ELANE | |
| SCHEMBL16859923 | 0.73 | KMT2A (0.51) | EP300MEN1KMT2ACYP2C19ELANE | |
| SCHEMBL7844009 | 0.73 | EP300 (0.66) | EP300MEN1KMT2ACYP2C19ELANE | |
| SCHEMBL66999 | 0.73 | MEN1 (0.51) | EP300MEN1KMT2ACYP2C19ELANE | |
| SCHEMBL1263711 | 0.72 | MEN1 (0.50) | EP300MEN1KMT2ACYP2C19ELANE | |
| SCHEMBL1264158 | 0.72 | MEN1 (0.50) | EP300MEN1KMT2ACYP2C19ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260776-A | PYRAZOLONE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |