Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312508 | 0.98 | CYP1A2 (0.48) | CYP1A2ERBB2FYNMAOAACHE | |
| Bromide SCHEMBL28027782 | 0.96 | CYP1A2 (0.47) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL201089 | 0.96 | CYP1A2 (0.47) | CYP1A2ERBB2FYNMAOAACHE | |
| Bromide SCHEMBL1470551 | 0.96 | CYP1A2 (0.47) | CYP1A2ERBB2FYNMAOAACHE | |
| Hydrochloric Acid SCHEMBL5318396 | 0.96 | CYP1A2 (0.47) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL18036614 | 0.88 | CYP1A2 (0.41) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL429607 | 0.86 | CYP1A2 (0.40) | CYP1A2ERBB2FYNMAOAACHE | |
| Bicarbonate SCHEMBL19435254 | 0.86 | ALDH1A1 (0.44) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL29741651 | 0.83 | CYP1A2 (0.40) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL28678826 | 0.83 | CYP1A2 (0.40) | CYP1A2ERBB2FYNMAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117181314-A | Preparation method and application method of Cu-based catalyst for preparing vinyl chloride by hydrochlorination of acetylene in fixed bed | 南开大学 | 2023-12-08 | — | — | CN | claimed |
| CN-115895395-B | Weather-resistant single-component epoxy emulsion and preparation method thereof | 衡水新光新材料科技有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-115895395-A | Weather-resistant single-component epoxy emulsion and preparation method thereof | 衡水新光新材料科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| US-4304946-A | METHANOL, CARBON MONOXIDE, COBALT SULFIDE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1981-12-08 | — | — | US | claimed |
| CN-118871501-A | Method for producing liquid crystalline resin | 宝理塑料株式会社 | 2024-10-29 | — | — | CN | disclosed |
| CN-114497426-B | Method for improving brightness of perovskite light-emitting diode and perovskite light-emitting diode | 南京工业大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-114262252-B | Method for preparing alkene and alkane by catalyzing alkyne with quaternary ammonium salt | 云南民族大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-117181314-A | Preparation method and application method of Cu-based catalyst for preparing vinyl chloride by hydrochlorination of acetylene in fixed bed | 南开大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-115895395-B | Weather-resistant single-component epoxy emulsion and preparation method thereof | 衡水新光新材料科技有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-115895395-A | Weather-resistant single-component epoxy emulsion and preparation method thereof | 衡水新光新材料科技有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-114497426-A | Method for improving brightness of perovskite light-emitting diode and perovskite light-emitting diode | 南京工业大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113307827-A | Aqueous phase synthesis method of tetraphenylphosphine phenolate | 山东师范大学实验厂 | 2021-08-27 | — | — | CN | disclosed |
| CN-113087627-A | Method for catalytically synthesizing 2, 4-dichloronitrobenzene by tetraphenyl phosphine iodide | 云南云天化股份有限公司 | 2021-07-09 | — | — | CN | disclosed |