Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5318396

Cl.Pc1cccc2ccc3cc4ccccc4cc3c12

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERBB2 known ✓ P04626 1/20 0.47
MAOA known ✓ P21397 1/20 0.47
ACHE known ✓ P22303 1/20 0.47
GAA known ✓ P10253 2/20 0.39
HTR2A known ✓ P28223 1/20 0.32
SIGMAR1 known ✓ Q99720 1/20 0.32
CYP1A2 P05177 4/20 0.47
FYN P06241 1/20 0.47
AHR P35869 1/20 0.47
ALDH1A1 P00352 12/20 0.41
HSD17B10 Q99714 10/20 0.41
HPGD P15428 6/20 0.41
HIF1A Q16665 4/20 0.41
CYP1B1 Q16678 2/20 0.41
THRB P10828 1/20 0.41
KDM4E B2RXH2 2/20 0.39
TSHR P16473 6/20 0.39
CASP1 P29466 3/20 0.39
MAPK1 P28482 3/20 0.39
CASP7 P55210 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL312508 0.98 CYP1A2 (0.48) CYP1A2ERBB2FYNMAOAACHE
Bromide SCHEMBL28027782 0.96 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL201089 0.96 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
Bromide SCHEMBL1470551 0.96 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
Iodide SCHEMBL11375908 0.96 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL18036614 0.88 CYP1A2 (0.41) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL429607 0.86 CYP1A2 (0.40) CYP1A2ERBB2FYNMAOAACHE
Bicarbonate SCHEMBL19435254 0.86 ALDH1A1 (0.44) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL29741651 0.83 CYP1A2 (0.40) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL28678826 0.83 CYP1A2 (0.40) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059836-A High-temperature-resistant rust-preventive oil and preparation method thereof 邢台禾大科技开发有限公司 2025-05-30 CN claimed
CN-119744352-A Intracellular ligation of photocatalysts for photoresponsive, probe-mediated protein labeling 美国锡德治疗有限公司 2025-04-01 CN claimed
CN-119555859-A High-sensitivity high-flux identification method for saccharide compounds based on chlorine enhanced ionization 北京大学 2025-03-04 CN claimed
CN-118937549-A Simultaneous mass spectrometry imaging method for halogenated alkane substances and biological metabolism small molecules 北京大学 2024-11-12 CN claimed
CN-118878853-A Synthesis method and application of porphyrin metal organic framework-based nanomaterial catalyst 安阳工学院 2024-11-01 CN claimed
CN-117181314-A Preparation method and application method of Cu-based catalyst for preparing vinyl chloride by hydrochlorination of acetylene in fixed bed 南开大学 2023-12-08 CN claimed
CN-116769465-A Antimony doped manganese-based organic-inorganic metal chloride luminescent material, synthesis and application 中国科学院大连化学物理研究所 2023-09-19 CN claimed
CN-113480703-B Method for preparing amphiphilic block copolymer by light-controlled free radical polymerization and ring-opening copolymerization 安阳工学院 2023-09-01 CN claimed
CN-114931147-A Oilfield bactericide and preparation method thereof 中海油(天津)油田化工有限公司 2022-08-23 CN claimed
CN-107803222-B Ruthenium complex catalyst for acetylene hydrochlorination 浙江工业大学 2020-06-09 CN claimed
CN-120059836-A High-temperature-resistant rust-preventive oil and preparation method thereof 邢台禾大科技开发有限公司 2025-05-30 CN disclosed
CN-119744352-A Intracellular ligation of photocatalysts for photoresponsive, probe-mediated protein labeling 美国锡德治疗有限公司 2025-04-01 CN disclosed
CN-119555859-A High-sensitivity high-flux identification method for saccharide compounds based on chlorine enhanced ionization 北京大学 2025-03-04 CN disclosed
CN-119219522-A Preparation method of 2, 4-difluorobenzonitrile 广西鲲宇药业有限公司 2024-12-31 CN disclosed
CN-118937549-A Simultaneous mass spectrometry imaging method for halogenated alkane substances and biological metabolism small molecules 北京大学 2024-11-12 CN disclosed
EP-1338588-B1 METHOD OF RESOLVING OPTICAL ISOMERS OF AMINO ACID DERIVATIVE TOKUYAMA CORP (JP) 2007-09-26 EP disclosed
US-7199264-B2 Method of resolving optical isomers of amino acid derivative TOKUYAMA CORPORATION (JP) 2007-04-03 US disclosed
US-20060258816-A1 Flame-retardant styrenic resin composition PS JAPAN CORPORATION (JP) 2006-11-16 US disclosed
US-20040102646-A1 Method of resolving optical isomers of amino acid derivative TOKUYAMA CORPORATION (JP) 2004-05-27 US disclosed
EP-1338588-A1 METHOD OF RESOLVING OPTICAL ISOMERS OF AMINO ACID DERIVATIVE TOKUYAMA CORPORATION (JP) 2003-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040102646-A1 Method of resolving optical isomers of amino acid derivative ALAD, AAAS, BCAT1 ERBB2 2361/4885MAOA 3811/4885ACHE 1712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.