Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27326726 | 0.79 | CNR1 (0.44) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL11770913 | 0.77 | PTPN22 (0.48) | — | |
| SCHEMBL9618295 | 0.77 | PTPN1 (0.44) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7110822 | 0.75 | GPR55 (0.48) | — | |
| SCHEMBL9575260 | 0.73 | ALDH1A1 (0.39) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL3200833 | 0.73 | HSD17B10 (0.35) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL2128362 | 0.72 | CYP1A2 (0.52) | KMT2AMEN1ALDH1A1HPGDTDP1 | |
| SCHEMBL29946522 | 0.69 | ABCG2 (0.50) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL29946524 | 0.69 | ABCG2 (0.50) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9517988 | 0.69 | GPR55 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288453-A | A-(1-PHENYL-2,2,2-TRIFLUOROETHOXY (OR -ETHYLTHIO))ALKANOIC ACIDS USEFUL AS ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | SCIENCE UNION ET CIE (FR) | 1981-09-08 | — | — | US | disclosed |