Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380544 | 0.92 | ADORA2B (0.59) | ADORA2BRXFP1MAPTLMNAADORA2A | |
| SCHEMBL11374923 | 0.86 | ADORA2B (0.62) | ADORA2BRXFP1MAPTLMNAADORA2A | |
| SCHEMBL11376320 | 0.85 | PDE1A (0.58) | ADORA2BADORA2A | |
| SCHEMBL11380455 | 0.84 | ADORA2B (0.54) | ADORA2BADORA1RXFP1MAPTLMNA | |
| SCHEMBL31482443 | 0.83 | ADORA2B (0.81) | ADORA2BRXFP1MAPTLMNAADORA2A | |
| SCHEMBL4384952 | 0.83 | ADORA2B (0.78) | ADORA2BRXFP1MAPTLMNAADORA2A | |
| SCHEMBL11381763 | 0.83 | ADORA2B (0.56) | ADORA2BRXFP1MAPTLMNA | |
| Dimethylamine SCHEMBL11381767 | 0.83 | SMN1; SMN2 (0.59) | ADORA2BRXFP1MAPTLMNAADORA2A | |
| SCHEMBL17748272 | 0.82 | ADORA1 (0.76) | ADORA2BADORA1RXFP1MAPTLMNA | |
| SCHEMBL19036787 | 0.82 | ADORA2B (0.69) | ADORA2BRXFP1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061753-A | Treating psoriasis with transient pro-drug forms of xanthine derivatives | INTERX RESEARCH CORPORATION (US) | 1977-12-06 | — | — | US | claimed |
| US-4275064-A | Transient pro-drug forms of xanthine derivatives and their use as topical anti-inflammatory agents | INTERX RESEARCH CORPORATION (US) | 1981-06-23 | — | — | US | disclosed |
| US-4061753-A | Treating psoriasis with transient pro-drug forms of xanthine derivatives | INTERX RESEARCH CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |