Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380544 | 0.85 | ADORA2B (0.59) | ADORA2BLMNAMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL11383851 | 0.85 | PDE1A (0.57) | ADORA2BLMNAPDE4APDE4BPDE4C | |
| Dimethazan SCHEMBL49056 | 0.84 | PDE4A (0.73) | ADORA2BLMNAMAPTPDE4APDE4B | |
| SCHEMBL11377411 | 0.83 | ADORA2B (0.59) | ADORA2BLMNAMAPTRXFP1 | |
| SCHEMBL11374923 | 0.82 | ADORA2B (0.62) | ADORA2BLMNAMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL683583 | 0.81 | ADORA2B (0.72) | ADORA2BLMNAMAPTPDE4APDE4B | |
| SCHEMBL19036787 | 0.81 | ADORA2B (0.69) | ADORA2BLMNAMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL11388656 | 0.81 | ADORA2B (0.55) | ADORA2BLMNAMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL23974589 | 0.79 | ADORA2B (0.66) | ADORA2BLMNAMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL13659055 | 0.79 | SMN1; SMN2 (0.66) | ADORA2BLMNAMAPTSMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275064-A | Transient pro-drug forms of xanthine derivatives and their use as topical anti-inflammatory agents | INTERX RESEARCH CORPORATION (US) | 1981-06-23 | — | — | US | disclosed |
| US-4061753-A | Treating psoriasis with transient pro-drug forms of xanthine derivatives | INTERX RESEARCH CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |