Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.43 |
| ▸ | PREP | P48147 | 3/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371154 | 0.83 | SIGMAR1 (0.43) | PREPUSP30MEN1KMT2ASIGMAR1 | |
| SCHEMBL11369577 | 0.83 | HTT (0.50) | DPP4MEN1KMT2AEPHX2SIGMAR1 | |
| SCHEMBL11381209 | 0.81 | PREP (0.58) | DPP4PREPMEN1KMT2ADPP8 | |
| SCHEMBL11380215 | 0.81 | DPP4 (0.50) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL11371767 | 0.80 | DPP4 (0.45) | DPP4PREPMEN1KMT2AMAPT | |
| SCHEMBL6957366 | 0.80 | PREP (0.53) | DPP4PREPMEN1KMT2ADPP8 | |
| SCHEMBL11373157 | 0.78 | PREP (0.49) | DPP4PREPDPP7POLB | |
| SCHEMBL11378197 | 0.76 | KDM4E (0.48) | MEN1KMT2AMAPTPOLB | |
| SCHEMBL11372497 | 0.76 | PREP (0.34) | DPP4PREPDPP8DPP9FAP | |
| SCHEMBL11383822 | 0.76 | DPP4 (0.41) | DPP4PREPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282212-A | Immune-stimulating 1-(N-acylcarbamoyl)-2-cyanoaziridines | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-04 | — | — | US | disclosed |