Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 9/20 | 0.34 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 5/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377543 | 0.76 | DPP4 (0.43) | PREPMAPTFAPDPP4DPP8 | |
| SCHEMBL11373179 | 0.71 | DPP4 (0.33) | PREPALDH1A1DPP4DPP8DPP9 | |
| SCHEMBL11380278 | 0.69 | ATF4 (0.50) | ALDH1A1MAPT | |
| SCHEMBL11371154 | 0.69 | SIGMAR1 (0.43) | PREPALDH1A1MAPTFAP | |
| SCHEMBL11369577 | 0.69 | HTT (0.50) | ALDH1A1MAPTHPGDFAPDPP4 | |
| SCHEMBL11371767 | 0.68 | DPP4 (0.45) | PREPALDH1A1GAAMAPTHPGD | |
| SCHEMBL11403893 | 0.68 | KDM4E (0.47) | CTPS1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL11378197 | 0.68 | KDM4E (0.48) | ALDH1A1MAPT | |
| SCHEMBL11369671 | 0.67 | KMT2A (0.50) | ALDH1A1GAAMAPTDPP4 | |
| SCHEMBL11373157 | 0.66 | PREP (0.49) | PREPGAADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282212-A | Immune-stimulating 1-(N-acylcarbamoyl)-2-cyanoaziridines | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-04 | — | — | US | disclosed |