Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.64 |
| ▸ | CA1 | P00915 | 4/20 | 0.64 |
| ▸ | CA2 | P00918 | 4/20 | 0.64 |
| ▸ | CA7 | P43166 | 4/20 | 0.64 |
| ▸ | CA9 | Q16790 | 4/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.64 |
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516254 | 0.86 | TSHR (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25386200 | 0.85 | ALDH1A1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10514703 | 0.83 | MAPK1 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11377261 | 0.83 | ALDH1A1 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13133486 | 0.83 | CA12 (0.66) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12345408 | 0.82 | EGFR (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8763431 | 0.82 | EGFR (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25385862 | 0.81 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10514738 | 0.81 | RAB9A (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10449048 | 0.80 | CA12 (0.77) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273773-A | IN COMBINATION WITH A DIURETIC | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-06-16 | — | — | US | disclosed |